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Catechins and Epigallocatechins

Catechins and Epigallocatechins are Flavonoid phytochemicals compounds found in green tea which also contains Polyphenols. Together, Catechins and Polyphenols comprise the active ingredients which have been found through numerous studies to possess strong antioxidant and anticarcinogenic abilities.

IMMUPRO™ contains the highest grade of green tea extract available on the market today with a guaranteed minimum 50% Epigallocatechins gallate.

Click the links below for further research on Green Tea

Jung YD, Kim MS, Shin BA, Chay KO, Ahn BW, Liu W, Bucana CD, Gallick GE, Ellis LM.
EGCG, a major component of green tea, inhibits tumour growth by inhibiting VEGF induction in human colon carcinoma cells. Br J Cancer. 2001 Mar 23;84(6):844-50. PMID: 11259102 [PubMed - indexed for MEDLINE]

Anderson RF, Fisher LJ, Hara Y, Harris T, Mak WB, Melton LD, Packer JE.
Green tea catechins partially protect DNA from (.)OH radical-induced strand breaks and base damage through fast chemical repair of DNA radicals. Carcinogenesis. 2001 Aug;22(8):1189-93. PMID: 11470748 [PubMed - in process]

Garbisa S, Sartor L, Biggin S, Salvato B, Benelli R, Albini A.
Tumor gelatinases and invasion inhibited by the green tea flavanol epigallocatechin-3-gallate. © 2001 American Cancer Society Cancer. 2001 Feb 15;91(4):822-32. PMID: 11241252 [PubMed - indexed for MEDLINE]

Osada K, Takahashi M, Hoshina S, Nakamura M, Nakamura S, Sugano M.
Tea catechins inhibit cholesterol oxidation accompanying oxidation of low density lipoprotein in vitro. Comp Biochem Physiol C Toxicol Pharmacol. 2001 Feb;128(2):153-64. PMID: 11239828 [PubMed - indexed for MEDLINE]

Muto S, Fujita K, Yamazaki Y, Kamataki T.
Inhibition by green tea catechins of metabolic activation of procarcinogens by human cytochrome P450. Mutat Res. 2001 Aug 8;479(1-2):197-206. PMID: 11470492 [PubMed - in process]

Uesato S, Kitagawa Y, Kamishimoto M, Kumagai A, Hori H, Nagasawa H.
Inhibition of green tea catechins against the growth of cancerous human colon and hepatic epithelial cells. Cancer Lett. 2001 Sep 10;170(1):41-4. PMID: 11448533 [PubMed - in process]

Varilek GW, Yang F, Lee EY, deVilliers WJ, Zhong J, Oz HS, Westberry KF, McClain CJ.
Green tea polyphenol extract attenuates inflammation in interleukin-2-deficient mice, a model of autoimmunity. J Nutr. 2001 Jul;131(7):2034-9. PMID: 11435526 [PubMed - in process]

Wong IY, He ZD, Huang Y, Chen ZY.
Antioxidative Activities of Phenylethanoid Glycosides from Ligustrum purpurascens. J Agric Food Chem. 2001 Jun;49(6):3113-9. PMID: 11410017 [PubMed - in process]

Lu YP, Lou YR, Lin Y, Shih WJ, Huang MT, Yang CS, Conney AH.
Inhibitory effects of orally administered green tea, black tea, and caffeine on skin carcinogenesis in mice previously treated with ultraviolet B light (high-risk mice): relationship to decreased tissue fat. Cancer Res. 2001 Jul 1;61(13):5002-9. PMID: 11431333 [PubMed - indexed for MEDLINE]

Liao S, Lin J, Dang MT, Zhang H, Kao YH, Fukuchi J, Hiipakka RA.
Growth suppression of hamster flank organs by topical application of catechins, alizarin, curcumin, and myristoleic acid. Arch Dermatol Res. 2001 Apr;293(4):200-5. PMID: 11380153 [PubMed - in process]

Inoue M, Tajima K, Mizutani M, Iwata H, Iwase T, Miura S, Hirose K, Hamajima N, Tominaga S.
Regular consumption of green tea and the risk of breast cancer recurrence: follow-up study from the Hospital-based Epidemiologic Research Program at Aichi Cancer Center (HERPACC), Japan. Cancer Lett. 2001 Jun 26;167(2):175-82. PMID: 11369139 [PubMed - indexed for MEDLINE]

Katiyar SK, Mukhtar H.
Green tea polyphenol (-)-epigallocatechin-3-gallate treatment to mouse skin prevents UVB-induced infiltration of leukocytes, depletion of antigen-presenting cells, and oxidative stress. J Leukoc Biol. 2001 May;69(5):719-26. PMID: 11358979 [PubMed - indexed for MEDLINE]

Shaw JC.
Green tea polyphenols may be useful in the treatment of androgen-mediated skin disorders. Arch Dermatol. 2001 May;137(5):664. No abstract available. PMID: 11346351 [PubMed - indexed for MEDLINE]

Riemersma RA, Rice-Evans CA, Tyrrell RM, Clifford MN, Lean ME.
Tea flavonoids and cardiovascular health. QJM. 2001 May;94(5):277-82. Review. PMID: 11353103 [PubMed - indexed for MEDLINE]

Smith DM, Dou QP.
Green tea polyphenol epigallocatechin inhibits DNA replication and consequently induces leukemia cell apoptosis. Int J Mol Med. 2001 Jun;7(6):645-52. PMID: 11351279 [PubMed - indexed for MEDLINE]

Katiyar SK, Elmets CA.
Green tea polyphenolic antioxidants and skin photoprotection (Review). Int J Oncol. 2001 Jun;18(6):1307-13. Review. PMID: 11351267 [PubMed - indexed for MEDLINE]

Metz N, Lobstein A, Schneider Y, Gosse F, Schleiffer R, Anton R, Raul F.
Suppression of azoxymethane-induced preneoplastic lesions and inhibition of cyclooxygenase-2 activity in the colonic mucosa of rats drinking a crude green tea extract. Nutr Cancer. 2000;38(1):60-4. PMID: 11341046 [PubMed - in process]

He P, Noda Y, Sugiyama K.
Green tea suppresses lipopolysaccharide-induced liver injury in d-galactosamine-sensitized rats. J Nutr. 2001 May;131(5):1560-7. PMID: 11340116 [PubMed - indexed for MEDLINE]

Ahmad N, Mukhtar H.
Cutaneous photochemoprotection by green tea: a brief review. Skin Pharmacol Appl Skin Physiol. 2001 Mar-Apr;14(2):69-76. Review. PMID: 11316965 [PubMed - indexed for MEDLINE

Opare Kennedy D, Kojima A, Hasuma T, Yano Y, Otani S, Matsui-Yuasa I.
Growth inhibitory effect of green tea extract and (-)-epigallocatechin in Ehrlich ascites tumor cells involves a cellular thiol-dependent activation of mitogenic-activated protein kinases. Chem Biol Interact. 2001 Apr 16;134(2):113-33. PMID: 11311209 [PubMed - indexed for MEDLINE]

Yokoyama S, Hirano H, Wakimaru N, Sarker KP, Kuratsu J.
Inhibitory effect of epigallocatechin-gallate on brain tumor cell lines in vitro. Neuro-oncol. 2001 Jan;3(1):22-8. PMID: 11305413 [PubMed - indexed for MEDLINE]

Setiawan VW, Zhang ZF, Yu GP, Lu QY, Li YL, Lu ML, Wang MR, Guo CH, Yu SZ, Kurtz RC, Hsieh CC.
Protective effect of green tea on the risks of chronic gastritis and stomach cancer. Int J Cancer. 2001 May 15;92(4):600-4. PMID: 11304697 [PubMed - indexed for MEDLINE

Hayakawa S, Kimura T, Saeki K, Koyama Y, Aoyagi Y, Noro T, Nakamura Y, Isemura M.
Apoptosis-inducing activity of high molecular weight fractions of tea extracts. Biosci Biotechnol Biochem. 2001 Feb;65(2):459-62. PMID: 11302190 [PubMed - in process]

Kennedy DO, Kojima A, Yano Y, Hasuma T, Otani S, Matsui-Yuasa I.
Growth inhibitory effect of green tea extract in Ehrlich ascites tumor cells involves cytochrome c release and caspase activation. Cancer Lett. 2001 May 10;166(1):9-15. PMID: 11295281 [PubMed - indexed for MEDLINE]

Hamilton-Miller JM.
Anti-cariogenic properties of tea (Camellia sinensis). J Med Microbiol. 2001 Apr;50(4):299-302. Review. PMID: 11289514 [PubMed - indexed for MEDLINE]

Pisters KM, Newman RA, Coldman B, Shin DM, Khuri FR, Hong WK, Glisson BS, Lee JS.
Phase I trial of oral green tea extract in adult patients with solid tumors. J Clin Oncol. 2001 Mar 15;19(6):1830-8. PMID: 11251015 [PubMed - indexed for MEDLINE]

Krul C, Luiten-Schuite A, Tenfelde A, van Ommen B, Verhagen H, Havenaar R.
Antimutagenic activity of green tea and black tea extracts studied in a dynamic in vitro gastrointestinal model. Mutat Res. 2001 Mar 1;474(1-2):71-85. PMID: 11239964 [PubMed - indexed for MEDLINE]

 

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